8QTW
Structure of human butyrylcholinesterase with (3-(((2-cycloheptylethyl)(methyl)amino)methyl)-1H-indol-7-yl)(methyl)carbamoylated Ser198
Summary for 8QTW
Entry DOI | 10.2210/pdb8qtw/pdb |
Descriptor | Cholinesterase, N-[3-[[2-cycloheptylethyl(methyl)amino]methyl]-1H-indol-7-yl]-N-methyl-methanamide, SULFATE ION, ... (12 entities in total) |
Functional Keywords | butyrylcholinesterase, inhibitor complex, carbamate, covalent, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 64309.95 |
Authors | Brazzolotto, X.,Meden, A.,Knez, D.,Gobec, S.,Nachon, F. (deposition date: 2023-10-13, release date: 2024-10-23) |
Primary citation | Brazzolotto, X.,Meden, A.,Knez, D.,Gobec, S.,Nachon, F. Structure of human butyrylcholinesterase with (3-(((2-cycloheptylethyl)(methyl)amino)methyl)-1H-indol-7-yl)(methyl)carbamoylated Ser198 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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