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8QTW

Structure of human butyrylcholinesterase with (3-(((2-cycloheptylethyl)(methyl)amino)methyl)-1H-indol-7-yl)(methyl)carbamoylated Ser198

Summary for 8QTW
Entry DOI10.2210/pdb8qtw/pdb
DescriptorCholinesterase, N-[3-[[2-cycloheptylethyl(methyl)amino]methyl]-1H-indol-7-yl]-N-methyl-methanamide, SULFATE ION, ... (12 entities in total)
Functional Keywordsbutyrylcholinesterase, inhibitor complex, carbamate, covalent, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight64309.95
Authors
Brazzolotto, X.,Meden, A.,Knez, D.,Gobec, S.,Nachon, F. (deposition date: 2023-10-13, release date: 2024-10-23)
Primary citationBrazzolotto, X.,Meden, A.,Knez, D.,Gobec, S.,Nachon, F.
Structure of human butyrylcholinesterase with (3-(((2-cycloheptylethyl)(methyl)amino)methyl)-1H-indol-7-yl)(methyl)carbamoylated Ser198
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.24 Å)
Structure validation

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PDB entries from 2024-11-20

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