8QTA

Cryo-EM structure of Streptococcus pneumoniae NADPH oxidase F397A mutant in complex with NADPH

Summary for 8QTA

Entry DOI	10.2210/pdb8qta/pdb
EMDB information	18647
Descriptor	FAD-binding FR-type domain-containing protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	nadph oxidase, ros producing, flavoprotein, heme protein, membrane protein
Biological source	Streptococcus pneumoniae
Total number of polymer chains	1
Total formula weight	48748.40
Authors	Dubach, V.R.A.,San Segundo-Acosta, P.,Murphy, B.J. (deposition date: 2023-10-12, release date: 2024-07-24, Last modification date: 2024-07-31)
Primary citation	Dubach, V.R.A.,San Segundo-Acosta, P.,Murphy, B.J. Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39039317 DOI: 10.1038/s41594-024-01348-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.64 Å)

Structure validation