8QRW
ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up)
Summary for 8QRW
Entry DOI | 10.2210/pdb8qrw/pdb |
Related | 8QRO 8QRP 8QRQ 8QRR 8QRS 8QRU 8QRV 8QRW |
EMDB information | 18621 18622 18623 18624 18625 18626 18627 18628 |
Descriptor | Neutral amino acid transporter B(0), SODIUM ION (2 entities in total) |
Functional Keywords | neutral amino acid exchanger amino acid transport system elevator transporter glutamine transport, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 57490.78 |
Authors | Borowska, A.,Rheinberger, J.,Paulino, C.,Slotboom, D.J. (deposition date: 2023-10-09, release date: 2024-08-14) |
Primary citation | Borowska, A.M.,Chiariello, M.G.,Garaeva, A.A.,Rheinberger, J.,Marrink, S.J.,Paulino, C.,Slotboom, D.J. Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15:6570-6570, 2024 Cited by PubMed: 39095408DOI: 10.1038/s41467-024-50888-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
Download full validation report