8QR2

Crystal structure of ERK2 in complex with a covalently bound macrocyclic ligand

Summary for 8QR2

• Entry DOI: 10.2210/pdb8qr2/pdb
• Descriptor: Mitogen-activated protein kinase 1, SULFATE ION, (4~{S},9~{S},10~{S},12~{E})-16-methoxy-4-methyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(18),12,14,16-tetraene-2,8-dione, ... (4 entities in total)
• Functional Keywords: serine-threonine-protein kinase, signaling protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 42868.18

Authors

Gelin, M.,Labesse, G. (deposition date: 2023-10-06, release date: 2025-04-16)

• Primary citation: Gelin, M.,Labesse, G.,Guichou, J.-F.,Pons, J.-L.,Barluenga, S.,Katickeyan, G.,Winssinger, N.; Crystal structure of ERK2 in complex with a covalently bound macrocyclic ligand; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)