8QQE

Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2

8QQE の概要

• エントリーDOI: 10.2210/pdb8qqe/pdb
• 分子名称: Meiotic recombination protein DMC1/LIM15 homolog, Breast cancer type 2 susceptibility protein, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: dna binding protein, meiotic recombination, ring protein, octamer, aaa atpase, recombination
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 80046.41

構造登録者

Miron, S.,Legrand, P.,Zinn-Justin, S. (登録日: 2023-10-04, 公開日: 2024-06-19)

• 主引用文献: Miron, S.,Legrand, P.,Dupaigne, P.,van Rossum-Fikkert, S.E.,Ristic, D.,Majeed, A.,Kanaar, R.,Zinn-Justin, S.,Zelensky, A.N.; DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.; Nucleic Acids Res., 2024; PubMed: 38828772; DOI: 10.1093/nar/gkae452

実験手法

X-RAY DIFFRACTION (3.461 Å)