8QOT
Structure of the mu opioid receptor bound to the antagonist nanobody NbE
Summary for 8QOT
Entry DOI | 10.2210/pdb8qot/pdb |
EMDB information | 18541 |
Descriptor | Mu-type opioid receptor, Nanobody E (NbE), NabFab HC, ... (5 entities in total) |
Functional Keywords | opioid receptor, nanobody, antagonist, nabfab, mor, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 5 |
Total formula weight | 143882.64 |
Authors | Yu, J.,Kumar, A.,Zhang, X.,Martin, C.,Raia, P.,Manglik, A.,Ballet, S.,Boland, A.,Stoeber, M. (deposition date: 2023-09-29, release date: 2023-12-27) |
Primary citation | Yu, J.,Kumar, A.,Zhang, X.,Martin, C.,Raia, P.,Koehl, A.,Laeremans, T.,Steyaert, J.,Manglik, A.,Ballet, S.,Boland, A.,Stoeber, M. Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist. Biorxiv, 2023 Cited by PubMed: 38106026DOI: 10.1101/2023.12.06.570395 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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