8QN5

M. tuberculosis salicylate synthase MbtI in complex with methyl-AMT (new crystal form)

This is a non-PDB format compatible entry.

Summary for 8QN5

• Entry DOI: 10.2210/pdb8qn5/pdb
• Descriptor: Salicylate synthase, 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, GLYCEROL, ... (6 entities in total)
• Functional Keywords: salicylate, isochorismate, chorismate, mycobactins, lyase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 4
• Total formula weight: 197643.09

Authors

Mori, M.,Villa, S.,Meneghetti, M.,Bellinzoni, M. (deposition date: 2023-09-25, release date: 2023-11-15, Last modification date: 2023-12-06)

• Primary citation: Mori, M.,Villa, S.,Chiarelli, L.R.,Meneghetti, F.,Bellinzoni, M.; Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery.; Pharmaceuticals, 16:-, 2023; PubMed: 38004425; DOI: 10.3390/ph16111559

Experimental method

X-RAY DIFFRACTION (1.544 Å)