8QN2

Helical foldamers as selective G-quadruplex ligands

Summary for 8QN2

• Entry DOI: 10.2210/pdb8qn2/pdb
• Descriptor: DNA (5'-D(*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*GP*GP*GP*T)-3'), ACE-QUK-QUK-ZY9-QUK, POTASSIUM ION, ... (5 entities in total)
• Functional Keywords: complex, foldamer, g-quadruplex, gene regulation
• Biological source: synthetic construct; More
• Total number of polymer chains: 3
• Total formula weight: 8320.90

Authors

Koenig, A.,Thore, S.,Gabelica, V. (deposition date: 2023-09-25, release date: 2025-04-09, Last modification date: 2025-12-17)

• Primary citation: Koenig, A.,Laffile, V.,Largy, E.,Thore, S.,Mackereth, C.,Ferrand, Y.,Gabelica, V.; Helical aromatic oligoamide foldamers as selective G-quadruplex ligands; Nucleic Acids Res., 2025; DOI: 10.1093/nar/gkaf1365

Experimental method

X-RAY DIFFRACTION (2.51 Å)