8QMT

Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+, succinic semialdehyde

8QMT の概要

• エントリーDOI: 10.2210/pdb8qmt/pdb
• 分子名称: Succinate semialdehyde dehydrogenase [NAD(P)+] Sad, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-oxobutanoic acid, ... (4 entities in total)
• 機能のキーワード: succinic semialdehyde, dehydrogenase, oxidoreductase
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 202257.07

構造登録者

He, H.,Zarzycki, J.,Erb, T.J. (登録日: 2023-09-25, 公開日: 2024-10-02)

• 主引用文献: He, H.,Gomez-Coronado, P.A.,Zarzycki, J.,Barthel, S.,Kahnt, J.,Claus, P.,Klein, M.,Klose, M.,de Crecy-Lagard, V.,Schindler, D.,Paczia, N.,Glatter, T.,Erb, T.J.; Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies; Nat Commun, 2024

実験手法

X-RAY DIFFRACTION (1.8 Å)