8QMB

Nucleant-assisted 2.0 A resolution structure of the Streptococcus pneumoniae topoisomerase IV-V18mer DNA complex with the novel fluoroquinolone Delafloxacin

8QMB の概要

• エントリーDOI: 10.2210/pdb8qmb/pdb
• 関連するPDBエントリー: 8C41
• 分子名称: DNA topoisomerase 4 subunit B,DNA topoisomerase 4 subunit A, ACETATE ION, FORMIC ACID, ... (13 entities in total)
• 機能のキーワード: protein-dna cleavage complex, topoisomerase iia, delafloxacin, topoisomerase iv-dna-antibiotic complex, isomerase, pegylated graphene
• 由来する生物種: Streptococcus pneumoniae; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 181444.30

構造登録者

Najmudin, S.,Pan, X.S.,Wang, B.,Chayen, N.E.,Fisher, L.M.,Sanderson, M.R. (登録日: 2023-09-21, 公開日: 2024-10-02)

• 主引用文献: Najmudin, S.,Pan, X.S.,Wang, B.,Chayen, N.E.,Fisher, L.M.,Sanderson, M.R.; The nature of the molecular interactions at high resolution of the Streptococcus pneumoniae topoisomerase IV-DNA complex with the novel fluoroquinolone Delafloxacin.; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)