8QM1

wild type Pa.FabF in complex cerulenin

Summary for 8QM1

Entry DOI	10.2210/pdb8qm1/pdb
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, FORMIC ACID, ... (6 entities in total)
Functional Keywords	inhibitor, transferase, fabf, complex, pseudomonas aeruginosa
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	89306.16
Authors	Georgiou, C.,Brenk, R.,Espeland, L.O. (deposition date: 2023-09-21, release date: 2024-01-10)
Primary citation	Georgiou, C.,Espeland, L.O.,Bukya, H.,Yadrykhinsky, V.,Haug, B.E.,Mainkar, P.,Brenk, R. New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-cwk25 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation