8QLT

Human MST3 (STK24) kinase in complex with inhibitor MR30

Summary for 8QLT

• Entry DOI: 10.2210/pdb8qlt/pdb
• Descriptor: Serine/threonine-protein kinase 24, 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: selective kinase inhibitors, structure-guided drug design, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35305.94

Authors

Balourdas, D.I.,Rak, M.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC) (deposition date: 2023-09-20, release date: 2023-11-08)

• Primary citation: Balourdas, D.I.,Rak, M.,Knapp, S.,Joerger, A.C.; Human MST3 (STK24) kinase in complex with inhibitor MR30; to be published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)