8QLR

Human MST3 (STK24) kinase in complex with inhibitor MR24

Summary for 8QLR

• Entry DOI: 10.2210/pdb8qlr/pdb
• Descriptor: Serine/threonine-protein kinase 24, 8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: selective kinase inhibitors, structure-guided drug design, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 70323.50

Authors

Balourdas, D.I.,Rak, M.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC) (deposition date: 2023-09-20, release date: 2023-11-08)

• Primary citation: Balourdas, D.I.,Rak, M.,Knapp, S.,Joerger, A.C.; Human MST3 (STK24) kinase in complex with inhibitor MR24; to be published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)