8QJ8

Structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with inhibitor

Summary for 8QJ8

Entry DOI	10.2210/pdb8qj8/pdb
Descriptor	Phosphopantetheine adenylyltransferase, 3-[3-(3-azanyl-2-cyano-phenyl)indol-1-yl]propanoic acid (3 entities in total)
Functional Keywords	coad, ppat, nucleotidyltransferase, transferase
Biological source	Mycobacteroides abscessus
Total number of polymer chains	3
Total formula weight	53346.65
Authors	Thomas, S.E.,McCarthy, W.J.,Coyne, A.G.,Blundell, T.L. (deposition date: 2023-09-12, release date: 2024-07-24)
Primary citation	McCarthy, W.J.,Thomas, S.E.,Olaleye, T.,Boland, J.A.,Floto, R.A.,Williams, G.,Blundell, T.L.,Coyne, A.G.,Abell, C. A fragment based competitive 19F LB-NMR platform for hotspot directed ligand profiling. Angew.Chem.Int.Ed.Engl., :e202406846-e202406846, 2024 Cited by PubMed: 38896426 DOI: 10.1002/anie.202406846 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.538 Å)

Structure validation