8QHE

Crystal structure IR-09

Summary for 8QHE

Entry DOI	10.2210/pdb8qhe/pdb
Descriptor	6-phosphogluconate dehydrogenase NADP-binding domain-containing protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ~{N}-methylcyclohexanamine, ... (5 entities in total)
Functional Keywords	reductase, biosynthetic protein
Biological source	Aspergillus lentulus
Total number of polymer chains	1
Total formula weight	33068.60
Authors	Levy, C.W. (deposition date: 2023-09-07, release date: 2023-10-11, Last modification date: 2023-10-25)
Primary citation	Casamajo, A.R.,Yu, Y.,Schnepel, C.,Morrill, C.,Barker, R.,Levy, C.W.,Finnigan, J.,Spelling, V.,Westerlund, K.,Petchey, M.,Sheppard, R.J.,Lewis, R.J.,Falcioni, F.,Hayes, M.A.,Turner, N.J. Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters. J.Am.Chem.Soc., 145:22041-22046, 2023 Cited by PubMed: 37782882 DOI: 10.1021/jacs.3c07010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation