8QH9

X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with a S-29b

Summary for 8QH9

• Entry DOI: 10.2210/pdb8qh9/pdb
• Descriptor: Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (8 entities in total)
• Functional Keywords: protein deacetylase, histone deacetylase 6, zinc binding group, inhibitor, danio rerio, hydrolase
• Biological source: Danio rerio (zebrafish)
• Total number of polymer chains: 1
• Total formula weight: 40874.68

Authors

Barinka, C.,Motlova, L. (deposition date: 2023-09-07, release date: 2024-08-07)

• Primary citation: Scheuerer, S.,Motlova, L.,Schaker-Hubner, L.,Sellmer, A.,Feller, F.,Ertl, F.J.,Koch, P.,Hansen, F.K.,Barinka, C.,Mahboobi, S.; Biological and structural investigation of tetrahydro-beta-carboline-based selective HDAC6 inhibitors with improved stability.; Eur.J.Med.Chem., 276:116676-116676, 2024; PubMed: 39067437; DOI: 10.1016/j.ejmech.2024.116676

Experimental method

X-RAY DIFFRACTION (1.59 Å)