8Q9Z

Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)

8Q9Z の概要

• エントリーDOI: 10.2210/pdb8q9z/pdb
• EMDBエントリー: 18290
• 分子名称: Gap junction beta-2 protein, DODECYL-BETA-D-MALTOSIDE, PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total)
• 機能のキーワード: gap junction large pore channel carbon dioxide sensitive, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 349094.44

構造登録者

Brotherton, D.H.,Cameron, A.D. (登録日: 2023-08-22, 公開日: 2024-06-12, 最終更新日: 2024-06-19)

• 主引用文献: Brotherton, D.H.,Nijjar, S.,Savva, C.G.,Dale, N.,Cameron, A.D.; Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.; Elife, 13:-, 2024; PubMed: 38829031; DOI: 10.7554/eLife.93686

実験手法

ELECTRON MICROSCOPY (2.4 Å)