8Q9Q

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC7 deacetylase binding motif

8Q9Q の概要

• エントリーDOI: 10.2210/pdb8q9q/pdb
• 分子名称: HDAC7 (histone deacetylase 7) binding motif peptide: GLY-VAL-VAL-LYS-GLN-LYS-LEU-ALA-GLU-VAL-ILE-LEU-LYS-LYS-GLN, MEF2D protein, MADS box dsDNA: AACTATTTATAAGA, ... (5 entities in total)
• 機能のキーワード: transcriptional repressor, transcription
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 32748.83

構造登録者

Chinellato, M.,Carli, A.,Perin, S.,Mazzocato, Y.,Biondi, B.,Di Giorgio, E.,Brancolini, C.,Angelini, A.,Cendron, L. (登録日: 2023-08-20, 公開日: 2024-04-17)

• 主引用文献: Chinellato, M.,Perin, S.,Carli, A.,Lastella, L.,Biondi, B.,Borsato, G.,Di Giorgio, E.,Brancolini, C.,Cendron, L.,Angelini, A.; Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.; J.Mol.Biol., 436:168541-168541, 2024; PubMed: 38492719; DOI: 10.1016/j.jmb.2024.168541

実験手法

X-RAY DIFFRACTION (2.11 Å)