8Q9N

Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V.

Summary for 8Q9N

• Entry DOI: 10.2210/pdb8q9n/pdb
• Descriptor: MEF2D protein, DNA MADS box, myocyte enhancer-binding factor 2-interacting transcriptional repressor (MITR or HDAC9) L151V mutant peptide: GLU-VAL-LYS-GLN-LYS-LEU-GLN-GLU-PHE-VAL-LEU-SER-LYS, ... (6 entities in total)
• Functional Keywords: transcriptional repressor, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 33221.23

Authors

Chinellato, M.,Carli, A.,Perin, S.,Mazzocato, Y.,Biondi, B.,Di Giorgio, E.,Brancolini, C.,Angelini, A.,Cendron, L. (deposition date: 2023-08-20, release date: 2024-06-26)

• Primary citation: Chinellato, M.,Perin, S.,Carli, A.,Lastella, L.,Biondi, B.,Borsato, G.,Di Giorgio, E.,Brancolini, C.,Cendron, L.,Angelini, A.; Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.; J.Mol.Biol., 436:168541-168541, 2024; PubMed: 38492719; DOI: 10.1016/j.jmb.2024.168541

Experimental method