8Q96
P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line
Summary for 8Q96
Entry DOI | 10.2210/pdb8q96/pdb |
EMDB information | 18269 |
Descriptor | Isoform Tau-E of Microtubule-associated protein tau, Unknown protein (3 entities in total) |
Functional Keywords | p301s tau, frontotemporal dementia and parkinsonism linked to chromosome 17, transgenic mice, electron cryo-microscopy, protein fibril |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 31481.08 |
Authors | Schweighauser, M.,Murzin, A.G.,Macdonald, J.,Lavenir, I.,Crowther, R.A.,Scheres, S.H.W.,Goedert, M. (deposition date: 2023-08-19, release date: 2023-10-11, Last modification date: 2023-10-18) |
Primary citation | Schweighauser, M.,Murzin, A.G.,Macdonald, J.,Lavenir, I.,Crowther, R.A.,Scheres, S.H.W.,Goedert, M. Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau. Acta Neuropathol Commun, 11:160-160, 2023 Cited by PubMed: 37798679DOI: 10.1186/s40478-023-01658-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.09 Å) |
Structure validation
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