8Q93

Crystal structure of the SARS-COV-2 RBD with neutralizing-VHHs Re30H02 and Re21D01

8Q93 の概要

• エントリーDOI: 10.2210/pdb8q93/pdb
• 分子名称: Spike protein S1, Nanobody Re21D01, Nanobody Re30H02 (3 entities in total)
• 機能のキーワード: neutralizing vhh, fold-promoter, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48617.90

構造登録者

Aksu, M.,Guttler, T.,Rymarenko, O.,Gorlich, D. (登録日: 2023-08-19, 公開日: 2023-12-20, 最終更新日: 2023-12-27)

• 主引用文献: Aksu, M.,Kumar, P.,Guttler, T.,Taxer, W.,Gregor, K.,Mussil, B.,Rymarenko, O.,Stegmann, K.M.,Dickmanns, A.,Gerber, S.,Reineking, W.,Schulz, C.,Henneck, T.,Mohamed, A.,Pohlmann, G.,Ramazanoglu, M.,Mese, K.,Gross, U.,Ben-Yedidia, T.,Ovadia, O.,Fischer, D.W.,Kamensky, M.,Reichman, A.,Baumgartner, W.,von Kockritz-Blickwede, M.,Dobbelstein, M.,Gorlich, D.; Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.; Antiviral Res., 221:105778-105778, 2023; PubMed: 38065245; DOI: 10.1016/j.antiviral.2023.105778

実験手法

X-RAY DIFFRACTION (3.1 Å)