8Q8S
Tau - AD-THF
Summary for 8Q8S
| Entry DOI | 10.2210/pdb8q8s/pdb |
| EMDB information | 18259 |
| Descriptor | Isoform Tau-D of Microtubule-associated protein tau (1 entity in total) |
| Functional Keywords | amyloid, tau, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 9 |
| Total formula weight | 360024.96 |
| Authors | Lovestam, S.,Li, D.,Scheres, S.H.W.,Goedert, M. (deposition date: 2023-08-18, release date: 2023-09-20, Last modification date: 2024-01-24) |
| Primary citation | Lovestam, S.,Li, D.,Wagstaff, J.L.,Kotecha, A.,Kimanius, D.,McLaughlin, S.H.,Murzin, A.G.,Freund, S.M.V.,Goedert, M.,Scheres, S.H.W. Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625:119-125, 2024 Cited by PubMed: 38030728DOI: 10.1038/s41586-023-06788-w PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.68 Å) |
Structure validation
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