8Q1Z
Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296
Summary for 8Q1Z
Entry DOI | 10.2210/pdb8q1z/pdb |
Descriptor | Serine/threonine-protein kinase VRK2, 2-[4-[[4-[(3-~{tert}-butyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]ethanenitrile (3 entities in total) |
Functional Keywords | inhibitor, kinase, vrk2, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37135.65 |
Authors | |
Primary citation | Wang, G.Q.,Amrhein, J.A.,Knapp, S. Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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