8PXU
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
Summary for 8PXU
| Entry DOI | 10.2210/pdb8pxu/pdb |
| Descriptor | Beta-N-acetylhexosaminidase, CACODYLATE ION (3 entities in total) |
| Functional Keywords | beta-hexosaminidase, akkermansia muciniphila, galnac-b converting, cbm, hydrolase |
| Biological source | Akkermansia muciniphila |
| Total number of polymer chains | 3 |
| Total formula weight | 220474.98 |
| Authors | Jensen, M.,Abou Hachem, M.,Morth, J.P. (deposition date: 2023-07-24, release date: 2024-02-28, Last modification date: 2024-05-15) |
| Primary citation | Jensen, M.,Stenfelt, L.,Ricci Hagman, J.,Pichler, M.J.,Weikum, J.,Nielsen, T.S.,Hult, A.,Morth, J.P.,Olsson, M.L.,Abou Hachem, M. Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 2024 Cited by PubMed: 38684911DOI: 10.1038/s41564-024-01663-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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