8PXI

Crystal structure of Endothiapepsin soaked with FRG283

8PXI の概要

• エントリーDOI: 10.2210/pdb8pxi/pdb
• 分子名称: Endothiapepsin, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: endothiapepsin, ligand complex, hydrolase
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34431.80

構造登録者

Mueller, J.M.,Eckelt, S.,Klebe, G.,Glinca, S. (登録日: 2023-07-23, 公開日: 2024-08-07, 最終更新日: 2026-01-14)

• 主引用文献: Huschmann, F.U.,Mueller, J.,Metz, A.,Ruf, M.,Senst, J.,Glinca, S.,Schiebel, J.,Heine, A.,Klebe, G.; Screening, Growing, and Validation by Catalog: Using Synthetic Intermediates from Natural Product Libraries to Discover Fragments for an Aspartic Protease Through Crystallography; Crystals, 14:755-, 2024; DOI: 10.3390/cryst14090755

実験手法

X-RAY DIFFRACTION (1.2 Å)