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8PWF

crystal structure of VDR in complex with Des-C-Ring and Aromatic-D-Ring analog 2

Summary for 8PWF
Entry DOI10.2210/pdb8pwf/pdb
DescriptorVitamin D3 receptor A, Nuclear receptor coactivator 2, (1R,3S,5Z)-4-methylidene-5-[(E)-3-[3-[7,7,7-tris(fluoranyl)-6-oxidanyl-6-(trifluoromethyl)heptyl]phenyl]pent-2-enylidene]cyclohexane-1,3-diol, ... (4 entities in total)
Functional Keywordsnuclear receptor, vdr, agonist, transcription
Biological sourceDanio rerio (zebrafish)
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Total number of polymer chains2
Total formula weight36147.06
Authors
rochel, N. (deposition date: 2023-07-20, release date: 2024-08-14)
Primary citationRochel, N.
Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR)
To Be Published,
Experimental method
Structure validation

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PDB entries from 2024-08-14

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