8PWD

Crystal structure of VDR in complex Des-C-Ring and Aromatic-D-Ring analog 3c

Summary for 8PWD

• Entry DOI: 10.2210/pdb8pwd/pdb
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 2, (1R,3S,5Z)-4-methylidene-5-[(E)-3-[3-[7,7,7-tris(fluoranyl)-6-oxidanyl-6-(trifluoromethyl)hept-3-ynyl]phenyl]pent-2-enylidene]cyclohexane-1,3-diol, ... (4 entities in total)
• Functional Keywords: nuclear receptor, vdr, agonist, transcription
• Biological source: Danio rerio (zebrafish); More
• Total number of polymer chains: 2
• Total formula weight: 36143.03

Authors

Rochel, N. (deposition date: 2023-07-20, release date: 2024-08-14)

• Primary citation: Rochel, N.; Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR); To Be Published,

Experimental method