8POT
Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole cmpd9 in the editing conformation
Summary for 8POT
Entry DOI | 10.2210/pdb8pot/pdb |
Related | 8POQ 8POR 8POS |
Descriptor | Leucine--tRNA ligase, tRNA(leu), 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | leucine trna ligase, atp binding protein, trna aminoacylation for protein translation, cytosolic reaction catalysed: atp + l-leucine + trna(leu) = amp + diphosphate + l-leucyl-trna(leu), ligase |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 2 |
Total formula weight | 128440.12 |
Authors | Palencia, A.,Hoffmann, G. (deposition date: 2023-07-05, release date: 2024-06-12, Last modification date: 2024-07-24) |
Primary citation | Hoffmann, G.,Lukarska, M.,Clare, R.H.,Masters, E.K.G.,Johnston, K.L.,Ford, L.,Turner, J.D.,Ward, S.A.,Taylor, M.J.,Jensen, M.R.,Palencia, A. Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host. Sci Adv, 10:eado1453-eado1453, 2024 Cited by PubMed: 38985862DOI: 10.1126/sciadv.ado1453 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.149 Å) |
Structure validation
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