8PMP

Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP

8PMP の概要

• エントリーDOI: 10.2210/pdb8pmp/pdb
• EMDBエントリー: 17763
• 分子名称: Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Serrate RNA effector molecule homolog, ... (4 entities in total)
• 機能のキーワード: nuclear cap-binding complex, ars2, pol ii transcript metabolism, rna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 191410.68

構造登録者

Dubiez, E.,Pellegrini, E.,Foucher, A.E.,Cusack, S.,Kadlec, J. (登録日: 2023-06-29, 公開日: 2024-01-17)

• 主引用文献: Dubiez, E.,Pellegrini, E.,Finderup Brask, M.,Garland, W.,Foucher, A.E.,Huard, K.,Heick Jensen, T.,Cusack, S.,Kadlec, J.; Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.; Cell Rep, 43:113639-113639, 2024; PubMed: 38175753; DOI: 10.1016/j.celrep.2023.113639

実験手法

ELECTRON MICROSCOPY (3.43 Å)