8PKO

The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).

Summary for 8PKO

• Entry DOI: 10.2210/pdb8pko/pdb
• EMDB information: 17749
• Descriptor: Green fluorescent protein,alpha-1,2-Mannosidase, Protein disulfide-isomerase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: mannosidase, disulfide isomerase, glycoprotein degradation, erad, misfolding, oxidoreductase
• Biological source: Thermochaetoides thermophila; More
• Total number of polymer chains: 2
• Total formula weight: 201025.00

Authors

Roversi, P.,Hitchman, C.J.,Lia, A.,Bayo, Y.,Gooptu, B. (deposition date: 2023-06-27, release date: 2024-07-10, Last modification date: 2025-09-24)

• Primary citation: Roversi, P.,Hitchman, C.J.,Lia, A.,Bayo, Y.; The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.6 Å)