8PKA
Structure of the human mitochondrial iron-sulfur cluster biosynthesis complex during persulfide transfer (without frataxin)
Summary for 8PKA
Entry DOI | 10.2210/pdb8pka/pdb |
EMDB information | 17734 |
Descriptor | Cysteine desulfurase, LYR motif-containing protein 4, Acyl carrier protein, ... (8 entities in total) |
Functional Keywords | cysteine desulfurase, fes biosynthesis, fes biogenesis, mitochondria, friedreich's ataxia, persulfide, frataxin, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 83613.04 |
Authors | |
Primary citation | Schulz, V.,Steinhilper, R.,Oltmanns, J.,Freibert, S.A.,Krapoth, N.,Linne, U.,Welsch, S.,Hoock, M.H.,Schunemann, V.,Murphy, B.J.,Lill, R. Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nat Commun, 15:3269-3269, 2024 Cited by PubMed: 38627381DOI: 10.1038/s41467-024-47310-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.75 Å) |
Structure validation
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