8PIV
Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1
Summary for 8PIV
Entry DOI | 10.2210/pdb8piv/pdb |
EMDB information | 17692 |
Descriptor | Glutamate receptor, Voltage-dependent calcium channel gamma-2 subunit, PALMITIC ACID, ... (6 entities in total) |
Functional Keywords | ampar, ion channels, neurotransmission, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 8 |
Total formula weight | 546488.38 |
Authors | Zhang, D.,Krieger, J.M.,Yamashita, K.,Greger, I.H. (deposition date: 2023-06-22, release date: 2023-08-30, Last modification date: 2023-10-11) |
Primary citation | Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Stockwell, I.,Baradaran, R.,Cais, O.,Greger, I.H. Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621:877-882, 2023 Cited by PubMed: 37704721DOI: 10.1038/s41586-023-06528-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.46 Å) |
Structure validation
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