8PIQ

Crystal Structure of BRD4-BD1 with BI894999

Summary for 8PIQ

• Entry DOI: 10.2210/pdb8piq/pdb
• Descriptor: Bromodomain-containing protein 4, ~{N},3-dimethyl-6-[6-(4-methylpiperazin-1-yl)-1-(phenylmethyl)benzimidazol-2-yl]-[1,2,4]triazolo[4,3-a]pyrazin-8-amine, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: boehringeringelheim, brd4, inhibitor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15769.22

Authors

Kessler, D. (deposition date: 2023-06-22, release date: 2023-07-26, Last modification date: 2025-02-05)

• Primary citation: Kessler, D.; Crystal Structure of BRD4-BD1 with BI894999; Not published,

Experimental method

X-RAY DIFFRACTION (1.117 Å)