8PF0

Diubiquitin-derived artificial binding protein (Affilin) variant Af1 specific to oncofetal fibronectin

Summary for 8PF0

• Entry DOI: 10.2210/pdb8pf0/pdb
• Descriptor: Affilin variant Af1 (77405), COPPER (II) ION, IMIDAZOLE, ... (4 entities in total)
• Functional Keywords: extra domain b, edb, oncofetal fibronectin, ubiquitin, diubiqutin, affilin, beta strand register shift, strand slippage, scaffold, artificial binding protein, plasticity, directed evolution, de novo protein
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 17921.46

Authors

Parthier, C.,Katzschmann, A.,Fiedler, E.,Haupts, U.,Reimann, A. (deposition date: 2023-06-15, release date: 2024-06-26)

• Primary citation: Katzschmann, A.,Fiedler, E.,Haupts, U.,Reimann, A.,Settele, F.,Gloser-Braeunig, M.,Parthier, C.; Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage; to be published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)