8PDJ
The phosphatase and C2 domains of SHIP1 with covalent Z56948267
This is a non-PDB format compatible entry.
Summary for 8PDJ
Entry DOI | 10.2210/pdb8pdj/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, 4-azanyl-3-fluoranyl-benzenethiol, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | ligand, phoshphatase, c2, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 53255.15 |
Authors | Bradshaw, W.J.,Moreira, T.,Pascoa, T.C.,Bountra, C.,Chalk, R.,von Delft, F.,Brennan, P.E.,Gileadi, O. (deposition date: 2023-06-12, release date: 2023-06-28, Last modification date: 2024-04-17) |
Primary citation | Bradshaw, W.J.,Kennedy, E.C.,Moreira, T.,Smith, L.A.,Chalk, R.,Katis, V.L.,Benesch, J.L.P.,Brennan, P.E.,Murphy, E.J.,Gileadi, O. Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 32:453-, 2024 Cited by PubMed: 38309262DOI: 10.1016/j.str.2024.01.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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