8P7D

CryoEM structure of METTL6 tRNA SerRS complex in a 1:1:2 stoichiometry

Summary for 8P7D

• Entry DOI: 10.2210/pdb8p7d/pdb
• Related: 8OWX 8OWY
• EMDB information: 17530
• Descriptor: tRNA N(3)-methylcytidine methyltransferase METTL6, Serine--tRNA ligase, cytoplasmic, Serine tRNA, ... (6 entities in total)
• Functional Keywords: mettl6, trna, serrs, serine trna, 3-methylcytosine, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 179100.44

Authors

Throll, P.,Dolce, L.G.,Kowalinski, E. (deposition date: 2023-05-30, release date: 2024-06-12, Last modification date: 2024-07-03)

• Primary citation: Throll, P.,G.Dolce, L.,Rico-Lastres, P.,Arnold, K.,Tengo, L.,Basu, S.,Kaiser, S.,Schneider, R.,Kowalinski, E.; Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-024-01341-3

Experimental method

ELECTRON MICROSCOPY (4.2 Å)