8P5R

Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA

Summary for 8P5R

• Entry DOI: 10.2210/pdb8p5r/pdb
• Descriptor: Multifunctional 2-oxoglutarate metabolism enzyme, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 2-oxoglutarate dehydrogenase; odh; kgd; oxidoreductase, oxidoreductase
• Biological source: Mycolicibacterium smegmatis MC2 155; More
• Total number of polymer chains: 16
• Total formula weight: 1488093.36

Authors

Wagner, T.,Mechaly, A.M.,Alzari, P.M.,Bellinzoni, M. (deposition date: 2023-05-24, release date: 2023-08-16, Last modification date: 2023-08-23)

• Primary citation: Yang, L.,Wagner, T.,Mechaly, A.,Boyko, A.,Bruch, E.M.,Megrian, D.,Gubellini, F.,Alzari, P.M.,Bellinzoni, M.; High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.; Nat Commun, 14:4851-4851, 2023; PubMed: 37563123; DOI: 10.1038/s41467-023-40253-6

Experimental method

X-RAY DIFFRACTION (4.562 Å)