8P5L
Kinase domain of mutant human ULK1 in complex with compound MRT67307
Summary for 8P5L
Entry DOI | 10.2210/pdb8p5l/pdb |
Related | 8P5G |
Descriptor | Serine/threonine-protein kinase ULK1, N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | autophagy, unc-like 1 kinase, transferase, kcgs |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65268.62 |
Authors | Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05) |
Primary citation | Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P. Crystal structures of ULK1 in complex with KCGS compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.836 Å) |
Structure validation
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