8P5K

Kinase domain of mutant human ULK1 in complex with compound MRT68921

Summary for 8P5K

• Entry DOI: 10.2210/pdb8p5k/pdb
• Related: 8P5G
• Descriptor: Serine/threonine-protein kinase ULK1, ~{N}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{H}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide, GLYCEROL, ... (6 entities in total)
• Functional Keywords: autophagy, unc-like 1 kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 130883.36

Authors

Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05)

• Primary citation: Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P.; Crystal structures of ULK1 in complex with KCGS compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.209 Å)