8P2M
C. elegans TIR-1 protein.
Summary for 8P2M
Entry DOI | 10.2210/pdb8p2m/pdb |
EMDB information | 17370 |
Descriptor | NAD(+) hydrolase tir-1 (1 entity in total) |
Functional Keywords | sarm1; tir-1; c. elegans; neurodegeneration; cryo-em; structural biology; nad+ metabolism; axon wallerian degeneration, hydrolase |
Biological source | Caenorhabditis elegans |
Total number of polymer chains | 9 |
Total formula weight | 760465.55 |
Authors | |
Primary citation | Khazma, T.,Grossman, A.,Guez-Haddad, J.,Feng, C.,Dabas, H.,Sain, R.,Weitman, M.,Zalk, R.,Isupov, M.N.,Hammarlund, M.,Hons, M.,Opatowsky, Y. Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Rep, 42:113026-113026, 2023 Cited by PubMed: 37635352DOI: 10.1016/j.celrep.2023.113026 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.82 Å) |
Structure validation
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