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8P1F

X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001909.

Summary for 8P1F
Entry DOI10.2210/pdb8p1f/pdb
DescriptorAcetylcholine-binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-1-phenyl-piperidine-4-carboxylic acid, ... (4 entities in total)
Functional Keywordsfragment based drug design, acetylcholine-binding protein, choline-binding proteins, choline-binding protein
Biological sourceLymnaea stagnalis (great pond snail)
Total number of polymer chains20
Total formula weight544742.91
Authors
Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (deposition date: 2023-05-12, release date: 2024-05-08, Last modification date: 2024-11-13)
Primary citationFitzgerald, E.A.,Cederfelt, D.,Boronat, P.,Aarmo Lund, B.,de Esch, I.J.P.,Danielson, U.H.
Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

227344

건을2024-11-13부터공개중

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