8P08

Crystal structure of human CLK1 in complex with Leucettinib-21

8P08 の概要

• エントリーDOI: 10.2210/pdb8p08/pdb
• 分子名称: Dual specificity protein kinase CLK1, (4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one (3 entities in total)
• 機能のキーワード: kinase, typ1 inhibitor, clk1, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39939.97

構造登録者

Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2023-05-09, 公開日: 2023-05-17, 最終更新日: 2024-06-19)

• 主引用文献: Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of human CLK1 bound in complex with Leucettinib-21; To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)