8OYP
Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic
Summary for 8OYP
Entry DOI | 10.2210/pdb8oyp/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 11,Response regulator FrzS, Polyubiquitin-B, CADMIUM ION, ... (8 entities in total) |
Functional Keywords | protease, ubiquitin, substrate complex, deubiquitinating enzyme, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 128747.73 |
Authors | Maurer, S.K.,Caulton, S.G.,Ward, S.J.,Emsley, J.,Dreveny, I. (deposition date: 2023-05-05, release date: 2023-10-18, Last modification date: 2023-11-15) |
Primary citation | Maurer, S.K.,Mayer, M.P.,Ward, S.J.,Boudjema, S.,Halawa, M.,Zhang, J.,Caulton, S.G.,Emsley, J.,Dreveny, I. Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299:105300-105300, 2023 Cited by PubMed: 37777157DOI: 10.1016/j.jbc.2023.105300 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.44 Å) |
Structure validation
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