8OY8

Time-resolved SFX structure of the class II photolyase complexed with a thymine dimer (30 nanosecond timepoint)

Summary for 8OY8

• Entry DOI: 10.2210/pdb8oy8/pdb
• Descriptor: Deoxyribodipyrimidine photo-lyase, CPD-COMPRISING OLIGONUCLEOTIDE, COUNTERSTRAND-OLIGONUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: dna binding protein, dna repair enzyme, flavoprotein, photoenzyme, lyase
• Biological source: Methanosarcina mazei Go1; More
• Total number of polymer chains: 6
• Total formula weight: 132875.81

Authors

Lane, T.J.,Christou, N.-E.,Melo, D.V.M.,Apostolopoulou, V.,Pateras, A.,Mashhour, A.R.,Galchenkova, M.,Gunther, S.,Reinke, P.,Kremling, V.,Oberthuer, D.,Henkel, A.,Sprenger, J.,Scheer, T.E.S.,Lange, E.,Yefanov, O.N.,Middendorf, P.,Sellberg, J.A.,Schubert, R.,Fadini, A.,Cirelli, C.,Beale, E.V.,Johnson, P.,Dworkowski, F.,Ozerov, D.,Bertrand, Q.,Wranik, M.,Zitter, E.D.,Turk, D.,Bajt, S.,Chapman, H.,Bacellar, C. (deposition date: 2023-05-03, release date: 2023-11-22, Last modification date: 2023-12-13)

• Primary citation: Christou, N.E.,Apostolopoulou, V.,Melo, D.V.M.,Ruppert, M.,Fadini, A.,Henkel, A.,Sprenger, J.,Oberthuer, D.,Gunther, S.,Pateras, A.,Rahmani Mashhour, A.,Yefanov, O.M.,Galchenkova, M.,Reinke, P.Y.A.,Kremling, V.,Scheer, T.E.S.,Lange, E.R.,Middendorf, P.,Schubert, R.,De Zitter, E.,Lumbao-Conradson, K.,Herrmann, J.,Rahighi, S.,Kunavar, A.,Beale, E.V.,Beale, J.H.,Cirelli, C.,Johnson, P.J.M.,Dworkowski, F.,Ozerov, D.,Bertrand, Q.,Wranik, M.,Bacellar, C.,Bajt, S.,Wakatsuki, S.,Sellberg, J.A.,Huse, N.,Turk, D.,Chapman, H.N.,Lane, T.J.; Time-resolved crystallography captures light-driven DNA repair.; Science, 382:1015-1020, 2023; PubMed: 38033070; DOI: 10.1126/science.adj4270

Experimental method

X-RAY DIFFRACTION (2.39 Å)