8OXV
Transglutaminase 3 zymogen in complex with DH patient-derived Fab DH63-B02
Summary for 8OXV
Entry DOI | 10.2210/pdb8oxv/pdb |
Descriptor | Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, Antibody Fab fragment Heavy chain, Antibody Fab fragment light chain, ... (7 entities in total) |
Functional Keywords | transglutaminase, tgm3, tg3, transglutaminase 3, enzyme, zymogen, antibody, dermatitis herpetiformis, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 124310.81 |
Authors | |
Primary citation | Heggelund, J.E.,Das, S.,Stamnaes, J.,Iversen, R.,Sollid, L.M. Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14:6216-6216, 2023 Cited by PubMed: 37798283DOI: 10.1038/s41467-023-42004-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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