8OXD

Structure of the human LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain bound with decasaccharide hyaluronan.

8OXD の概要

• エントリーDOI: 10.2210/pdb8oxd/pdb
• 分子名称: Lymphatic vessel endothelial hyaluronic acid receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: hyaluronan binding, cell migration, lymphatic system, cell adhesion
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17922.30

構造登録者

Ni, T.,Banerji, N.,Jackson, D.J.,Gilbert, R.J.C. (登録日: 2023-05-01, 公開日: 2024-11-13, 最終更新日: 2025-03-26)

• 主引用文献: Bano, F.,Banerji, S.,Ni, T.,Green, D.E.,DeAngelis, P.L.,Paci, E.,Lepsik, M.,Jackson, D.J.,Gilbert, R.J.C.; Structure of the murine LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain in an unliganded state; Nature Communications, 2025

実験手法

X-RAY DIFFRACTION (1.32 Å)