8OWY
Crystal structure of METTL6 mutant 40-269 bound to SAH
Summary for 8OWY
Entry DOI | 10.2210/pdb8owy/pdb |
Descriptor | tRNA N(3)-methylcytidine methyltransferase METTL6, S-ADENOSYL-L-HOMOCYSTEINE (2 entities in total) |
Functional Keywords | trna modification, m3c, methyltransferase, rna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 56083.94 |
Authors | Throll, P.,Basu, S.,Dolce, L.G.,Kowalinski, E. (deposition date: 2023-04-28, release date: 2024-05-08, Last modification date: 2024-07-10) |
Primary citation | Throll, P.,G Dolce, L.,Rico-Lastres, P.,Arnold, K.,Tengo, L.,Basu, S.,Kaiser, S.,Schneider, R.,Kowalinski, E. Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38918637DOI: 10.1038/s41594-024-01341-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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