8OWX

Crystal Structure of METTL6 bound to SAH

8OWX の概要

• エントリーDOI: 10.2210/pdb8owx/pdb
• 分子名称: tRNA N(3)-methylcytidine methyltransferase METTL6, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• 機能のキーワード: trna modification, m3c, methyltransferase, rna binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65744.95

構造登録者

Throll, P.,Basu, S.,Dolce, L.G.,Kowalinski, E. (登録日: 2023-04-28, 公開日: 2024-05-08, 最終更新日: 2024-07-03)

• 主引用文献: Throll, P.,G.Dolce, L.,Rico-Lastres, P.,Arnold, K.,Tengo, L.,Basu, S.,Kaiser, S.,Schneider, R.,Kowalinski, E.; Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-024-01341-3

実験手法

X-RAY DIFFRACTION (2.601 Å)