8OU2

Crystal structure of the bromodomain of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to a potent inhibitor

8OU2 の概要

• エントリーDOI: 10.2210/pdb8ou2/pdb
• 分子名称: Nucleosome-remodeling factor subunit BPTF, 7-(1-cyclopropylpyrazol-4-yl)-2-[[2-fluoranyl-4-(4-methylpiperazin-1-yl)sulfonyl-phenyl]amino]-3-methyl-pyrido[1,2-a]pyrimidin-4-one, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: nucleosome-remodeling factor subunit bptf, inhibitor, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30558.71

構造登録者

Balikci, E.,Ni, X.,Bountra, C.,von Delft, F.,Huber, K. (登録日: 2023-04-21, 公開日: 2024-05-01)

• 主引用文献: Balikci, E.,Ni, X.,Bountra, C.,von Delft, F.,Huber, K.; Crystal structure of the bromodomain of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to a potent inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)