8ORO

CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) S101A VARIANT COMPLEXED WITH 2-METHYL-QUINOLIN-4(1H)-ONE UNDER HYPEROXYC CONDITIONS

This is a non-PDB format compatible entry.

Summary for 8ORO

• Entry DOI: 10.2210/pdb8oro/pdb
• Descriptor: 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, OXYGEN MOLECULE, ... (7 entities in total)
• Functional Keywords: alpha-beta hydrolase complex, oxidoreductase, dioxygenase, cofactor-devoid
• Biological source: Paenarthrobacter nitroguajacolicus
• Total number of polymer chains: 2
• Total formula weight: 67644.58

Authors

Bui, S.,Steiner, R.A. (deposition date: 2023-04-15, release date: 2024-01-17)

• Primary citation: Bui, S.,Gil-Guerrero, S.,van der Linden, P.,Carpentier, P.,Ceccarelli, M.,Jambrina, P.G.,Steiner, R.A.; Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold.; Chem Sci, 14:10547-10560, 2023; PubMed: 37799987; DOI: 10.1039/d3sc03044j

Experimental method

X-RAY DIFFRACTION (2 Å)